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Creators/Authors contains: "Xiao, Feifei"

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  1. ; ; ; (, Statistics in Biosciences)
    null (Ed.)
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  2. ; ; ; ; ; ; ; ; (, Bioinformatics)
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  3. ; ; ; ; ; (, Bioinformatics)
    Hancock, John (Ed.)
    Abstract SummaryChromosomal copy number variation (CNV) refers to a polymorphism that a DNA segment presents deletion or duplication in the population. The computational algorithms developed to identify this type of variation are usually of high computational complexity. Here we present a user-friendly R package, modSaRa, designed to perform copy number variants identification. The package is developed based on a change-point based method with optimal computational complexity and desirable accuracy. The current version of modSaRa package is a comprehensive tool with integration of preprocessing steps and main CNV calling steps. Availability and ImplementationmodSaRa is an R package written in R, C ++ and Rcpp and is now freely available for download at http://c2s2.yale.edu/software/modSaRa. Supplementary informationSupplementary data are available at Bioinformatics online. 
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